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DES(1-3)GF-1

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IGF-1 DES 1, 3 is a modified, naturally occurring version of insulin-like growth factor-1 (IGF-1), characterized by its truncated structure. This variant is present in the brain, breast milk, and uterine tissues and plays a role in stimulating both hypertrophy and hyperplasia across different cell types. Studies have revealed that IGF-1 DES is more potent than standard IGF-1, primarily due to its improved bioavailability. Researchers are currently investigating its potential applications in treating inflammatory bowel disease (IBD), autism, and various neurological disorders. Evidence suggests that IGF-1 DES is beneficial for maintaining synaptic health in the central nervous system and, like traditional IGF-1, supports the regeneration of muscle and connective tissues.