Hexarelin
Hexarelin is a synthetic peptide that mimics the effects of ghrelin by binding to and activating the ghrelin (GHS) receptor. This peptide is known for its cardioprotective, anti-fibrotic, antihypertensive, and anti-fertility properties. In studies involving animal models of heart attack, hexarelin has been shown to safeguard cardiac function. In hypertensive rats, it reduces collagen buildup, lowers the expression of TIMP-1, collagen I, and collagen III, while boosting MMP2 and MMP9 levels, leading to decreased cardiac fibrosis, lower blood pressure, and reduced left ventricular hypertrophy. Additionally, hexarelin has been found to reduce ovulation and limit reproduction in vivo.
